Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 13/20 | 0.78 |
| ▸ | TUBB4A | P04350 | 12/20 | 0.78 |
| ▸ | TUBB | P07437 | 12/20 | 0.78 |
| ▸ | TUBA3C | P0DPH7 | 12/20 | 0.78 |
| ▸ | TUBA1B | P68363 | 12/20 | 0.78 |
| ▸ | TUBA4A | P68366 | 12/20 | 0.78 |
| ▸ | TUBB4B | P68371 | 12/20 | 0.78 |
| ▸ | TUBB3 | Q13509 | 12/20 | 0.78 |
| ▸ | TUBB2A | Q13885 | 12/20 | 0.78 |
| ▸ | TUBB8 | Q3ZCM7 | 12/20 | 0.78 |
| ▸ | TUBA3E | Q6PEY2 | 12/20 | 0.78 |
| ▸ | TUBA1A | Q71U36 | 12/20 | 0.78 |
| ▸ | TUBA1C | Q9BQE3 | 12/20 | 0.78 |
| ▸ | TUBB6 | Q9BUF5 | 12/20 | 0.78 |
| ▸ | TUBB2B | Q9BVA1 | 12/20 | 0.78 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13438471 | 0.93 | TUBB4A (0.87) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13622254 | 0.91 | TUBB1 (0.83) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13622177 | 0.90 | TUBB4A (0.81) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401451 | 0.90 | TUBB4A (0.81) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13438472 | 0.89 | TUBB4A (0.93) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401534 | 0.88 | TUBB4A (0.78) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401466 | 0.87 | TUBB4A (0.77) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401535 | 0.87 | TUBB4A (0.77) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401578 | 0.85 | TUBB1 (0.74) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13438470 | 0.85 | TUBB4A (0.84) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622612-B2 | Tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2009-11-24 | — | — | US | disclosed |
| US-7622612-B2 | Tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2009-11-24 | — | — | US | disclosed |
| US-20070021427-A1 | Novel tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2007-01-25 | — | — | US | disclosed |
| US-20070021427-A1 | Novel tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021427-A1 | Novel tricyclic derivatives and their use | NFATC1, IL2, CCL2 | TUBB1 14/4885TUBB4A 45/4885TUBB 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.