Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 11/20 | 0.42 |
| ▸ | CTSS | P25774 | 7/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19361663 | 1.00 | CA1 (0.44) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL25315586 | 1.00 | CA1 (0.44) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL23743602 | 0.86 | CTSK (0.43) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL19084258 | 0.85 | CA1 (0.53) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL31510003 | 0.82 | AAK1 (0.49) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL25755528 | 0.82 | PPARA (0.53) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL25755539 | 0.82 | CTSK (0.40) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL12265061 | 0.82 | PPARA (0.53) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL22506799 | 0.82 | PPARA (0.53) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL23743600 | 0.81 | CTSK (0.40) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268607-B9 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2015-05-13 | — | — | EP | disclosed |
| EP-2268607-B1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2015-02-18 | — | — | EP | disclosed |
| WO-2009113828-A9 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2009-11-05 | — | — | WO | disclosed |
| WO-2009113828-A2 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2009-09-17 | — | — | WO | disclosed |