SCHEMBL13622664

SCHEMBL13622664

N#Cc1ccccc1N1CCC(CC(=O)O)CC1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 9/20 0.56
CHRM4 P08173 1/20 0.54
DRD2 P14416 4/20 0.51
DRD4 P21917 4/20 0.51
FFAR1 O14842 1/20 0.50
GRM5 P41594 1/20 0.48
PDE4B Q07343 2/20 0.45
DRD3 P35462 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL1024810 0.92 FFAR4 (0.55) FFAR4CHRM4DRD2DRD4FFAR1
SCHEMBL31042529 0.87 CHRM4 (0.50) FFAR4CHRM4DRD2DRD4GRM5
SCHEMBL3607872 0.87 AR (0.59) FFAR4FFAR1
SCHEMBL2559433 0.86 CHRM4 (0.57) FFAR4CHRM4DRD2DRD4GRM5
SCHEMBL31042536 0.86 CHRM4 (0.57) FFAR4CHRM4DRD2DRD4GRM5
SCHEMBL2558173 0.84 FFAR4 (0.47) FFAR4CHRM4DRD2DRD4FFAR1
SCHEMBL31042543 0.84 CHRM4 (0.55) FFAR4CHRM4DRD2DRD4GRM5
SCHEMBL30164232 0.82 CHRM4 (0.56) CHRM4DRD2DRD4GRM5DRD3
SCHEMBL7520833 0.82 CHRM4 (0.49) CHRM4DRD2DRD4GRM5DRD3
SCHEMBL31042537 0.82 CHRM4 (0.46) FFAR4CHRM4DRD2DRD4GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660188-A1 COMPOSITION FOR PREVENTING OR TREATING CANCER DISEASES COMPRISING ARYL-PIPERIDINE DERIVATIVE Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162805-A1 COMPOSITION FOR PREVENTING OR TREATING CANCER DISEASES COMPRISING ARYL-PIPERIDINE DERIVATIVE 한국화학연구원 2024-08-08 WO disclosed
US-8871753-B2 Macrocyclic compounds and their use as kinase inhibitors INCYTE CORPORATION (US) 2014-10-28 US disclosed
US-8871753-B2 Macrocyclic compounds and their use as kinase inhibitors INCYTE CORPORATION (US) 2014-10-28 US disclosed
US-20090286778-A1 MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS INCYTE CORPORATION (US) 2009-11-19 US disclosed
US-20090286778-A1 MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS INCYTE CORPORATION (US) 2009-11-19 US disclosed
WO-2009132202-A2 MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS INCYTE CORPORATION (US) 2009-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286778-A1 MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS JAK2, JAK1, ALK FFAR4 2075/4885CHRM4 4834/4885DRD2 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.