Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803482 | 0.82 | OPRM1 (0.56) | GRIN2BOPRM1OPRL1BCHEACHE | |
| SCHEMBL2378639 | 0.79 | GRIN2B (0.50) | GRIN2BOPRM1OPRL1BCHEACHE | |
| SCHEMBL30942832 | 0.78 | GRIN2B (0.43) | GRIN2BOPRM1OPRL1BCHEACHE | |
| SCHEMBL24350665 | 0.78 | GRIN2B (0.49) | GRIN2BOPRM1OPRL1BCHEACHE | |
| SCHEMBL2376300 | 0.78 | OPRM1 (0.51) | GRIN2BOPRM1OPRL1BCHEACHE | |
| SCHEMBL26347105 | 0.78 | OPRM1 (0.51) | GRIN2BOPRM1OPRL1BCHEACHE | |
| SCHEMBL13819197 | 0.75 | FUCA1 (0.45) | GRIN2BOPRM1OPRL1SIGMAR1 | |
| SCHEMBL1134382 | 0.75 | FUCA1 (0.42) | GRIN2BOPRM1OPRL1SIGMAR1 | |
| SCHEMBL30532010 | 0.75 | FUCA1 (0.45) | GRIN2BOPRM1OPRL1SIGMAR1 | |
| SCHEMBL3507722 | 0.75 | FUCA1 (0.45) | GRIN2BOPRM1OPRL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136850-A1 | MUSCARINIC RECEPTOR AGONITS USEFUL IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | WO | disclosed |