Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622679 | 0.88 | MCHR1 (0.49) | MCHR1SCD | |
| SCHEMBL13622724 | 0.86 | MCHR1 (0.46) | MCHR1F10HTR2AHTR2CHTR2B | |
| SCHEMBL13622942 | 0.85 | MCHR1 (0.46) | MCHR1F10SCD | |
| SCHEMBL13622680 | 0.85 | MCHR1 (0.48) | MCHR1SCD | |
| SCHEMBL13623308 | 0.79 | HTR2C (0.36) | MCHR1HTR2AHTR2CHTR2B | |
| SCHEMBL4455857 | 0.77 | SLC6A2 (0.34) | MCHR1HTR2CHTR2BDPP4 | |
| SCHEMBL13622867 | 0.75 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL13622868 | 0.75 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL4457815 | 0.73 | MCHR1 (0.50) | MCHR1SCDHTR2AHTR2C | |
| SCHEMBL4444619 | 0.73 | MCHR1 (0.43) | MCHR1SCDHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137270-A2 | AZETIDINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-11-12 | — | — | WO | disclosed |