Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457815 | 0.86 | MCHR1 (0.50) | MCHR1HTR2CHTR2A | |
| SCHEMBL13622717 | 0.86 | MCHR1 (0.50) | MCHR1HTR2CHTR2BDPP4HTR2A | |
| SCHEMBL4444619 | 0.85 | MCHR1 (0.43) | MCHR1HTR2CHTR2BALDH1A1ALOX15 | |
| SCHEMBL13622939 | 0.83 | MCHR1 (0.45) | MCHR1F10 | |
| SCHEMBL4455857 | 0.82 | SLC6A2 (0.34) | MCHR1HTR2CHTR2BDPP4 | |
| SCHEMBL4456061 | 0.81 | MCHR1 (0.42) | MCHR1F10 | |
| SCHEMBL4444373 | 0.80 | MCHR1 (0.41) | MCHR1F10 | |
| SCHEMBL13623308 | 0.77 | HTR2C (0.36) | MCHR1HTR2CHTR2BHTR2A | |
| SCHEMBL4451742 | 0.76 | MCHR1 (0.34) | MCHR1HTR2CHTR2B | |
| SCHEMBL4443651 | 0.73 | MCHR1 (0.46) | MCHR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137270-A2 | AZETIDINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-11-12 | — | — | WO | disclosed |