Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12140598 | 1.00 | CTSV (0.53) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13622726 | 1.00 | CTSV (0.53) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL16313095 | 1.00 | CTSV (0.53) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL16316240 | 1.00 | CTSV (0.53) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL14522202 | 1.00 | CTSV (0.53) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL12601219 | 1.00 | CTSV (0.53) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13251405 | 0.97 | CTSV (0.58) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8282346 | 0.91 | CTSV (0.44) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8254688 | 0.90 | CTSV (0.43) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13632837 | 0.88 | CTSV (0.56) | CTSVCTSLCTSBELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619094-B2 | Ketoamides with cyclic P4's as inhibitors of NS3 serine protease of hepatitis C virus | SCHERING CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |