Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456061 | 0.94 | MCHR1 (0.42) | MCHR1F10CYP3A4CYP2C19 | |
| SCHEMBL4443651 | 0.91 | MCHR1 (0.46) | MCHR1F10CYP3A4CYP2C19 | |
| SCHEMBL4457815 | 0.88 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL4444373 | 0.85 | MCHR1 (0.41) | MCHR1F10 | |
| SCHEMBL4444619 | 0.85 | MCHR1 (0.43) | MCHR1 | |
| SCHEMBL13622724 | 0.83 | MCHR1 (0.46) | MCHR1F10 | |
| SCHEMBL13622868 | 0.81 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL4448473 | 0.80 | AVPR2 (0.36) | MCHR1 | |
| SCHEMBL13622680 | 0.77 | MCHR1 (0.48) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL4444404 | 0.76 | MCHR1 (0.52) | MCHR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137270-A2 | AZETIDINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-11-12 | — | — | WO | disclosed |