SCHEMBL13623015

SCHEMBL13623015

CCOC(=O)c1ccc(-c2ccc(OC(=O)CC)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.60
KMT2A Q03164 3/20 0.60
HIF1A Q16665 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
RECQL P46063 1/20 0.60
ELANE P08246 1/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
ESR2 Q92731 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CYP1A2 P05177 3/20 0.53
KCNH2 Q12809 2/20 0.53
MEN1 O00255 2/20 0.53
SLC22A2 O15244 1/20 0.53
TMPRSS2 O15393 1/20 0.53
F2 P00734 1/20 0.53
F10 P00742 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10624301 0.97 KMT2A (0.57) ESR1KMT2AHIF1ASMN1; SMN2RECQL
SCHEMBL1638836 0.87 CA12 (0.58) ESR1KMT2ASMN1; SMN2RECQLCA12
SCHEMBL10421856 0.86 LMNA (0.60) ESR1KMT2AHIF1ASMN1; SMN2RECQL
SCHEMBL9171166 0.84 KMT2A (0.68) ESR1KMT2AHIF1ASMN1; SMN2RECQL
SCHEMBL1965326 0.84 CA1 (0.73) ESR1KMT2ASMN1; SMN2RECQLCA12
SCHEMBL16351874 0.84 CA1 (0.73) ESR1KMT2ASMN1; SMN2RECQLCA12
SCHEMBL10423314 0.84 MAPT (0.62) ESR1KMT2AHIF1ASMN1; SMN2RECQL
SCHEMBL10422534 0.83 MAPK1 (0.52) ESR1KMT2AHIF1ASMN1; SMN2RECQL
SCHEMBL10344282 0.83 PRSS1 (0.69) ESR1KMT2ARECQLCA12CA1
SCHEMBL14544912 0.83 ESR1 (0.72) ESR1KMT2ASMN1; SMN2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619803-B2 Electrochromic display element and full-color electrochromic display element KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-17 US disclosed
US-20090027757-A1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-29 US disclosed