SCHEMBL13623253

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13623258	0.87	HPGD (0.41)	HSD17B3HPGDSRD5A1ADRA2AADRA2B
	SCHEMBL13623260	0.87	HPGD (0.41)	HSD17B3HPGDSRD5A1ADRA2AADRA2B
	SCHEMBL2208353	0.85	HPGD (0.46)	HSD17B3HPGDADRA2AADRA2BADRA2C
	SCHEMBL13158706	0.85	HSD17B3 (0.41)	HSD17B3HPGDSRD5A1ADRA2AADRA2B
	SCHEMBL14281334	0.85	HPGD (0.59)	HSD17B3HPGDADRA2AADRA2BADRA2C
	SCHEMBL12414461	0.84	HSD17B3 (0.46)	HSD17B3HPGDSRD5A1ADRA2AADRA2B
	SCHEMBL14595498	0.84	HSD17B3 (0.46)	HSD17B3HPGDSRD5A1ADRA2AADRA2B
	SCHEMBL6123811	0.84	HPGD (0.56)	HSD17B3HPGDSRD5A1ADRA2AADRA2B
	SCHEMBL12414465	0.84	HPGD (0.42)	HSD17B3HPGDADRA2AADRA2BADRA2C
	SCHEMBL13623251	0.83	HSP90AA1 (0.45)	HSD17B3HPGDSRD5A1ALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.