SCHEMBL2208353

SCHEMBL2208353

c1ccc2c(c1)CCc1ccccc1N2c1ccc(-c2ccc(N3c4ccccc4CCc4ccccc43)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.46
ADRA2B P18089 2/20 0.42
ADRA2C P18825 2/20 0.42
ADRA2A P08913 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CDK4 P11802 1/20 0.41
ALOX15 P16050 1/20 0.41
CCND1 P24385 1/20 0.41
HSD17B3 P37058 2/20 0.41
HTR2A P28223 2/20 0.40
TSHR P16473 1/20 0.39
NPC1 O15118 1/20 0.39
MITF O75030 1/20 0.39
RAB9A P51151 1/20 0.39
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12414465 0.94 HPGD (0.42) HPGDADRA2BADRA2CADRA2AMEN1
SCHEMBL12992625 0.93 HPGD (0.50) HPGDADRA2BADRA2CADRA2AMEN1
SCHEMBL14595498 0.91 HSD17B3 (0.46) HPGDADRA2BADRA2CADRA2AMEN1
SCHEMBL12414461 0.91 HSD17B3 (0.46) HPGDADRA2BADRA2CADRA2AMEN1
SCHEMBL23584371 0.89 HPGD (0.39) HPGDADRA2BADRA2CADRA2AMEN1
SCHEMBL6123837 0.87 HPGD (0.55) HPGDADRA2BADRA2CADRA2AMEN1
SCHEMBL14281334 0.86 HPGD (0.59) HPGDADRA2BADRA2CADRA2AMEN1
SCHEMBL13623253 0.85 HSD17B3 (0.48) HPGDADRA2BADRA2CADRA2AFAAH
SCHEMBL25956521 0.85 KDM4E (0.47) HPGDADRA2BADRA2CADRA2AMEN1
SCHEMBL25477396 0.84 ADRA2A (0.41) HPGDADRA2BADRA2CADRA2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022725-B2 Electronic device, light-emitting device, electronic appliance, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-06-25 US disclosed
US-12022725-B2 Electronic device, light-emitting device, electronic appliance, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-06-25 US disclosed
US-11342504-B2 Oxocarbon-, pseudooxocarbon- and radialene compounds and their use NOVALED GMBH (DE) 2022-05-24 US disclosed
US-20210257562-A1 Electronic Device, Light-Emitting Device, Electronic Appliance, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-08-19 US disclosed
US-10950805-B2 Electronic device, light-emitting device, electronic appliance, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-03-16 US disclosed
US-20200176692-A1 Electronic Device, Light-Emitting Device, Electronic Appliance, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-06-04 US disclosed
US-20200152873-A1 Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use NOVALED GMBH (DE) 2020-05-14 US disclosed
US-10586926-B2 Oxocarbon-, pseudooxocarbon- and radialene compounds and their use NOVALED GMBH (DE) 2020-03-10 US disclosed
US-20180076389-A1 Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use NOVALED GMBH (DE) 2018-03-15 US disclosed
US-9876172-B2 Oxocarbon-, pseudooxocarbon- and radialene compounds and their use NOVALED GMBH (DE) 2018-01-23 US disclosed
US-20150097146-A1 Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use NOVALED GMBH (DE) 2015-04-09 US disclosed
US-8911645-B2 Oxocarbon-, pseudooxocarbon- and radialene compounds and their use NOVALED AG (DE) 2014-12-16 US disclosed
US-20140070145-A1 Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use NOVALED AG (DE) 2014-03-13 US disclosed
US-8617426-B2 Oxocarbon-, pseudooxocarbon- and radialene compounds and their use NOVALED AG (DE) 2013-12-31 US disclosed
US-20110309309-A1 Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use NOVALED AG (DE) 2011-12-22 US disclosed
US-7981324-B2 Oxocarbon-, pseudooxocarbon- and radialene compounds and their use NOVALED AG (DE) 2011-07-19 US disclosed
EP-2262030-A2 Organic light emitting device THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2010-12-15 EP disclosed
US-20080265216-A1 Use as doping agent for doping organic semiconductive matrix material, as blocker material, as charge injection layer, as electrode material as well as organic semiconductor, electronic component; 1,3-Bi(dicyanomethylene)indane-2-ylidene-bis(4-oxo-[3,5-di-t-butyl]-2,5-cyclohexadienylidene)cyclopropane NOVALED AG (DE) 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210257562-A1 Electronic Device, Light-Emitting Device, Electronic Appliance, and Lighting Device EED, L1CAM, ALDH1A2 HPGD 3907/4885ADRA2B 2283/4885ADRA2C 1812/4885
US-20180076389-A1 Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use DNMT3B, CHRNB1, CHRNB2 HPGD 3283/4885ADRA2B 49/4885ADRA2C 166/4885
US-12022725-B2 Electronic device, light-emitting device, electronic appliance, and lighting device EED, L1CAM, ALDH1A2 HPGD 3907/4885ADRA2B 2283/4885ADRA2C 1812/4885
US-20200176692-A1 Electronic Device, Light-Emitting Device, Electronic Appliance, and Lighting Device EED, L1CAM, ALDH1A2 HPGD 3907/4885ADRA2B 2283/4885ADRA2C 1812/4885
US-20200152873-A1 Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use DNMT3B, CHRNB1, CHRNB2 HPGD 3283/4885ADRA2B 49/4885ADRA2C 166/4885
US-10586926-B2 Oxocarbon-, pseudooxocarbon- and radialene compounds and their use DNMT3B, CHRNB1, CHRNB2 HPGD 3283/4885ADRA2B 49/4885ADRA2C 166/4885
US-10950805-B2 Electronic device, light-emitting device, electronic appliance, and lighting device EED, L1CAM, ALDH1A2 HPGD 3907/4885ADRA2B 2283/4885ADRA2C 1812/4885
US-11342504-B2 Oxocarbon-, pseudooxocarbon- and radialene compounds and their use DNMT3B, CHRNB1, CHRNB2 HPGD 3283/4885ADRA2B 49/4885ADRA2C 166/4885
US-20110309309-A1 Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use DNMT3B, CHRNB1, CHRNB2 HPGD 3283/4885ADRA2B 49/4885ADRA2C 166/4885
US-20080265216-A1 Use as doping agent for doping organic semiconductive matrix material, as blocker material, as charge injection layer, as electrode material as well as organic semiconductor, electronic component; 1,3-Bi(dicyanomethylene)indane-2-ylidene-bis(4-oxo-[3,5-di-t-butyl]-2,5-cyclohexadienylidene)cyclopropane CHRNB1, GJB2, CHRNB3 HPGD 3829/4885ADRA2B 40/4885ADRA2C 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.