Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12166154 | 1.00 | ALDH1A1 (0.40) | ALDH1A1CYP3A4KDM4EKMT2AMAPT | |
| SCHEMBL14509057 | 0.80 | HCRTR2 (0.42) | ALDH1A1CYP3A4KDM4EKMT2AMAPT | |
| SCHEMBL12166285 | 0.80 | HCRTR2 (0.42) | ALDH1A1CYP3A4KDM4EKMT2AMAPT | |
| SCHEMBL12267702 | 0.77 | ACACB (0.40) | CYP3A4 | |
| SCHEMBL407689 | 0.77 | TDP1 (0.43) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL440195 | 0.77 | TDP1 (0.43) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL19853295 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CYP3A4KDM4EKMT2AMAPT | |
| SCHEMBL12166160 | 0.74 | CHEK2 (0.40) | — | |
| SCHEMBL14509054 | 0.74 | S1PR5 (0.50) | ALDH1A1CYP3A4KDM4EKMT2AMAPT | |
| SCHEMBL12267641 | 0.74 | S1PR5 (0.50) | ALDH1A1CYP3A4KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622496-B2 | antiarrhythmia agents; 1-(2-Amino-acetyl)-4-(benzoylamino)-pyrrolidine-2-carboxylic acid; desirable bioavailability properties | ZEALAND PHARMA A/S (DK) | 2009-11-24 | — | — | US | disclosed |