Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997187 | 0.92 | ABL1 (0.42) | ABL1 | |
| SCHEMBL8997123 | 0.90 | ABL1 (0.42) | ABL1 | |
| SCHEMBL8997099 | 0.90 | ABL1 (0.48) | ABL1 | |
| SCHEMBL13788397 | 0.87 | ABL1 (0.46) | ABL1 | |
| SCHEMBL1358290 | 0.86 | ABL1 (0.60) | ABL1 | |
| SCHEMBL8997132 | 0.86 | ABL1 (0.46) | ABL1 | |
| SCHEMBL8997217 | 0.86 | ABL1 (0.47) | ABL1 | |
| SCHEMBL8997246 | 0.85 | ABL1 (0.39) | ABL1 | |
| SCHEMBL8997452 | 0.85 | ABL1 (0.42) | ABL1 | |
| SCHEMBL8997304 | 0.84 | ABL1 (0.46) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618974-B2 | Gyrase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-11-17 | — | — | US | disclosed |
| US-7618974-B2 | Gyrase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-11-17 | — | — | US | disclosed |