Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997193 | 0.89 | ABL1 (0.42) | ABL1 | |
| SCHEMBL8997132 | 0.88 | ABL1 (0.46) | ABL1 | |
| SCHEMBL8997217 | 0.88 | ABL1 (0.47) | ABL1 | |
| SCHEMBL13623305 | 0.87 | ABL1 (0.43) | ABL1 | |
| SCHEMBL8997388 | 0.87 | ABL1 (0.41) | ABL1 | |
| SCHEMBL8997187 | 0.86 | ABL1 (0.42) | ABL1 | |
| SCHEMBL1358290 | 0.86 | ABL1 (0.60) | ABL1 | |
| SCHEMBL8997123 | 0.85 | ABL1 (0.42) | ABL1 | |
| SCHEMBL8997099 | 0.84 | ABL1 (0.48) | ABL1 | |
| SCHEMBL13752510 | 0.82 | ABL1 (0.48) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592686-B1 | GYRASE INHIBITORS AND USES THEREOF | VERTEX PHARMA (US) | 2009-07-08 | — | — | EP | disclosed |