Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 7/20 | 0.43 |
| ▸ | HBB | P68871 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461518 | 0.82 | ADORA2A (0.38) | LMNACYP3A4SMN1; SMN2 | |
| Acyclovir SCHEMBL8052815 | 0.71 | PNP (0.68) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14383603 | 0.71 | PNP (0.71) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9068089 | 0.70 | BLM (0.73) | BLMMEN1KMT2AALDH1A1LMNA | |
| Acyclovir SCHEMBL5930213 | 0.69 | PNP (0.60) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2340330 | 0.68 | BLM (0.73) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14137223 | 0.68 | PNP (0.51) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10046637 | 0.67 | BLM (0.69) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL16063286 | 0.67 | POLB (0.65) | PNPHPRT1POLG | |
| SCHEMBL6263150 | 0.67 | ALDH1A1 (0.41) | BLMMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286973-A1 | LIGAND-CONJUGATED MONOMERS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286973-A1 | LIGAND-CONJUGATED MONOMERS | TNFSF11, BCDIN3D, CD40LG | BLM 3687/4885MEN1 1993/4885KMT2A 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.