SCHEMBL1362395

SCHEMBL1362395

Cc1ccc(Oc2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.55
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
PTGS2 P35354 1/20 0.45
BRD4 O60885 2/20 0.44
GSTP1 P09211 1/20 0.43
SYK P43405 1/20 0.43
HDAC7 Q8WUI4 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
TTR P02766 1/20 0.42
PSMB5 P28074 1/20 0.41
ADORA1 P30542 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21258336 0.95 PTGDR2 (0.54) PTGDR2NCOA1NCOA3PTGS2BRD4
SCHEMBL2858335 0.93 PTGDR2 (0.54) PTGDR2NCOA1NCOA3PTGS2BRD4
Phosphoric Acid SCHEMBL35596 0.91 PTGDR2 (0.55) PTGDR2NCOA1NCOA3PTGS2BRD4
Phosphoric Acid SCHEMBL29381893 0.91 PTGDR2 (0.55) PTGDR2NCOA1NCOA3PTGS2BRD4
SCHEMBL10898179 0.90 PTGDR2 (0.60) PTGDR2NCOA1NCOA3SYKHDAC7
SCHEMBL1298462 0.87 PTGDR2 (0.57) PTGDR2NCOA1NCOA3SYKHDAC7
SCHEMBL9228881 0.87 NCOA1 (0.49) PTGDR2NCOA1NCOA3PTGS2BRD4
SCHEMBL14027215 0.86 NCOA1 (0.49) PTGDR2NCOA1NCOA3GSTP1ALDH1A1
Phosphoric Acid SCHEMBL3682881 0.85 PTGDR2 (0.52) PTGDR2NCOA1NCOA3PTGS2GSTP1
SCHEMBL14003484 0.83 SYK (0.54) PTGDR2GSTP1SYKALDH1A1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230061187-A1 METHOD FOR GRAPHENE INCORPORATION INTO A RUBBER COMPOUNDING BY USING LIQUID PLASTICIZER ROUTE - LPR METHOD FORD GLOBAL TECHNOLOGIES, LLC (US) 2023-03-02 US claimed
US-7018558-B2 Method of improving performance of refrigerant systems COGNIS CORPORATION (US) 2006-03-28 US claimed
US-20030220430-A1 A vulcanizable rubber comprising a acrylonitrile-butadiene-styrene terpolymers and a polar plasticizer; for making a molded tire BAYER AKTIENGESELLSCHAFT (DE) 2003-11-27 US claimed
US-6551523-B1 Esters formed from neopentylglycol and/or pentaerythritol and 2-ethylhexanoic acid; for use with chlorine-free fluids such as pentafluoroethylene COGNIS CORPORATION 2003-04-22 US claimed
EP-0205995-B1 LUBRICANT AND ITS USE RWE-DEA Aktiengesellschaft für Mineraloel und Chemie (DE) 1992-01-15 EP claimed
US-20240117232-A1 DROP-IN RECYCLED REFRIGERANT COMPOSITIONS HAVING NO NET GWP BEING A DROP-IN REPLACEMENT FOR R-32 AND R-454B THE COULAN COMPANY, L.L.C. (US) 2024-04-11 US disclosed
US-11760865-B2 Halogen-free sulphonic acid ester and/or sulphinic acid ester as flame retardant, flame retardant synergists and radical generators in plastics Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-09-19 US disclosed
US-11746271-B1 Drop-in recycled refrigerant compositions having no net GWP The Coulan Company L.L.C. (US) 2023-09-05 US disclosed
US-11655407-B1 Drop-in recycled refrigerant compositions having no net GWP replacing R-410A THE COULAN COMPANY, L.L.C. (US) 2023-05-23 US disclosed
US-20230061187-A1 METHOD FOR GRAPHENE INCORPORATION INTO A RUBBER COMPOUNDING BY USING LIQUID PLASTICIZER ROUTE - LPR METHOD FORD GLOBAL TECHNOLOGIES, LLC (US) 2023-03-02 US disclosed
EP-3983468-A1 NON-COMBUSTIBLE WATERBORNE SELF LEVELLING EPOXY FLOOR Sika Technology AG (CH) 2022-04-20 EP disclosed
WO-2022060772-A1 ENVIRONMENTALLY FRIENDLY REFRIGERANT COMPOSITIONS FLUOROFUSION SPECIALTY CHEMICALS, INC. (US) 2022-03-24 WO disclosed
US-4397974-A Low-halogen-content, thermoplastic polyurethane elastomer having improved flame resistance by the addition of a 4-component additive combination, its production and its use BAYER AKTIENGESELLSCHAFT (DE) 1983-08-09 US disclosed
EP-0019926-A1 Thermoformable carpet backing composition and a process of making a carpet UNION CARBIDE CORPORATION (US) 1980-12-10 EP disclosed
US-4129696-A XEROSOL, SILICATE BAYER AKTIENGESELLSCHAFT (DE) 1978-12-12 US disclosed
US-4055694-A Starch latex composition REICHHOLD CHEMICALS, INC. (US) 1977-10-25 US disclosed
US-4026931-A AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT BAYER AKTIENGESELLSCHAFT (DT) 1977-05-31 US disclosed
US-4015970-A FERTILIZER WITH POLYMERIC COATING AIRWICK INDUSTRIES, INC. (US) 1977-04-05 US disclosed
US-3993619-A AZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1976-11-23 US disclosed
US-3984379-A POLYMERIZATION CATALYSTS TEIJIN LIMITED (JA) 1976-10-05 US disclosed