Phosphoric Acid

Phosphoric Acid

SCHEMBL35596

Cc1ccc(Oc2ccccc2)c(-c2ccccc2)c1.O=P(O)(O)O

nearest known ligand 0.55

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.55
GPR84 Q9NQS5 1/20 0.48
HDAC7 Q8WUI4 1/20 0.47
PTGS2 P35354 1/20 0.42
BRD4 O60885 3/20 0.42
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
PLA2G1B P04054 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
TTR P02766 3/20 0.40
GSTP1 P09211 1/20 0.40
FFAR4 Q5NUL3 2/20 0.39
HCRTR1 O43613 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL29381893 1.00 PTGDR2 (0.55) PTGDR2GPR84HDAC7PTGS2BRD4
Phosphoric Acid SCHEMBL3682881 0.94 PTGDR2 (0.52) PTGDR2GPR84HDAC7PTGS2NCOA1
Phosphoric Acid SCHEMBL8846394 0.91 CYP3A4 (0.47) PTGDR2GPR84HDAC7PTGS2NCOA1
SCHEMBL1362395 0.91 PTGDR2 (0.55) PTGDR2HDAC7PTGS2BRD4NCOA1
Phosphoric Acid SCHEMBL4388891 0.89 BRD4 (0.43) PTGDR2PTGS2BRD4MEN1KMT2A
SCHEMBL2858335 0.88 PTGDR2 (0.54) PTGDR2HDAC7PTGS2BRD4NCOA1
Triclofos SCHEMBL10459071 0.86 PTGDR2 (0.45) PTGDR2GPR84HDAC7MEN1KMT2A
SCHEMBL21258336 0.85 PTGDR2 (0.54) PTGDR2HDAC7PTGS2BRD4NCOA1
Phosphoric Acid SCHEMBL3681623 0.82 PTGDR2 (0.49) PTGDR2GPR84HDAC7PTGS2BRD4
SCHEMBL10898179 0.82 PTGDR2 (0.60) PTGDR2HDAC7NCOA1NCOA3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3186 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630777-B2 Liquid and semisolid lubricant compositions, methods of making, and uses thereof UNIVERSITY OF NORTH TEXAS (US) 2026-05-19 US claimed
EP-3658616-B1 HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS FRAUNHOFER GES FORSCHUNG (DE) 2025-10-22 EP claimed
US-12415905-B2 Flame-retardant thermoplastic polyurethane BASF SE (DE) 2025-09-16 US claimed
EP-4001357-B1 VINYL CHLORIDE RESIN COMPOSITION FOR WALLPAPER HANWHA SOLUTIONS CORP (KR) 2025-07-09 EP claimed
EP-3833703-B2 PHOSPHINATE AS FLAME PROTECTION ADDITIVE FOR PUR/PIR RIGID FOAMS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-30 EP claimed
US-20250101330-A1 LIQUID AND SEMISOLID LUBRICANT COMPOSITIONS, METHODS OF MAKING, AND USES THEREOF Board of Trustees of Illinois State University 2025-03-27 US claimed
EP-4524172-A1 PIR AND PUR-PIR POLYOL COMPOSITION PCC ROKITA Spolka Akcyjna (PL) 2025-03-19 EP claimed
CN-119505509-A Flame-retardant polycarbonate composite material and preparation method thereof 北京理工大学 2025-02-25 CN claimed
WO-2024248312-A1 POLYOL COMPOSITION FOR PRODUCING RIGID POLYURETHANE FOAM 롯데케미칼 주식회사 2024-12-05 WO claimed
CN-119000954-A Method for determining diphenyl phosphate and diphenyl phosphate in consumer goods 深圳天祥质量技术服务有限公司 2024-11-22 CN claimed
US-4440833-A PHENOLIC RESIN, POLYETHERURETHANE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1984-04-03 US claimed
US-4299883-A Method of making a sound-absorbent material, and material so made ROTH JACQUES 1981-11-10 US claimed
US-4232788-A Auto-expansible cushioning bag ROTH JACQUES 1980-11-11 US claimed
US-4182706-A Flame-retardant agents for phenolic resins and process for their production CHEMISCHE FABRIK KALK GMBH (DE) 1980-01-08 US claimed
US-4115207-A Separation of phenol-, cyclohexanone-, and cyclohexylbenzene-containing mixtures employing a trisubstituted phosphate PHILLIPS PETROLEUM COMPANY (US) 1978-09-19 US claimed
US-4074015-A Process for the production of nonflammable laminated materials DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1978-02-14 US claimed
US-4056656-A PHENOLIC RESIN, PENTABROMODIPHENYL ETHER, PLASTICIZER DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-01 US claimed
US-3994835-A Process for the production of colored polyurethane foams BAYER AKTIENGESELLSCHAFT (DT) 1976-11-30 US claimed
US-3971744-A PLASTICIZERS, HYDROPHILIC FILLERS CESKOSLOVENSKA AKADEMIE VED (CS) 1976-07-27 US claimed
US-3944688-A Method for the manufacture of water-repellent, fire-resistant nonwoven fabrics PENNWALT CORPORATION (US) 1976-03-16 US claimed