Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070283 | 0.83 | KMT2A (0.47) | GSK3BALDH1A1HPGDF2DAO | |
| SCHEMBL4393404 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HPGDPOLBCASP3SENP8 | |
| SCHEMBL7003234 | 0.75 | F2 (0.42) | GSK3BALDH1A1HPGDPOLBCASP3 | |
| SCHEMBL25080938 | 0.69 | SMN1; SMN2 (0.39) | KMT2ARAB9AHTTSMN1; SMN2MEN1 | |
| SCHEMBL1024697 | 0.68 | F2 (0.43) | GSK3BALDH1A1HPGDPOLBCASP3 | |
| SCHEMBL486042 | 0.68 | DAO (0.48) | GSK3BALDH1A1HPGDPOLBCASP3 | |
| SCHEMBL8189892 | 0.68 | POLB (0.40) | GSK3BALDH1A1HPGDPOLBF2 | |
| SCHEMBL11008232 | 0.68 | KMT2A (0.39) | ALDH1A1HPGDPOLBDAOKMT2A | |
| SCHEMBL27935754 | 0.68 | ALDH1A1 (0.42) | GSK3BALDH1A1HPGDPOLBCASP3 | |
| SCHEMBL4239545 | 0.67 | ALDH1A1 (0.50) | GSK3BALDH1A1HPGDF2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |