Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524752 | 0.80 | GRIN1 (0.37) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL3912213 | 0.79 | IDH1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10045761 | 0.79 | IDH1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL13412438 | 0.79 | IDH1 (0.34) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL12973889 | 0.78 | IDH1 (0.33) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12973852 | 0.78 | IDH1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL12973868 | 0.77 | IDH1 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5737415 | 0.77 | IDH1 (0.33) | — | |
| SCHEMBL13930594 | 0.76 | ALDH1A1 (0.36) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL12973946 | 0.76 | IDH1 (0.33) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140932-A2 | METHOD OF PRODUCING (3R,4S)-L-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)- HYDROXYPROPYL)]-4-(4-HYDROXYPHENYL)-2-AZETIDINONE | ZENTIVA, K.S. (CZ) | 2009-11-26 | — | — | WO | disclosed |