Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624993 | 0.89 | STAT6 (0.67) | SYKSTAT6 | |
| SCHEMBL13624768 | 0.84 | SYK (0.70) | SYKSTAT6 | |
| SCHEMBL1355118 | 0.83 | SYK (0.82) | SYK | |
| SCHEMBL1352394 | 0.82 | SYK (1.00) | SYK | |
| SCHEMBL1352399 | 0.82 | SYK (1.00) | SYK | |
| SCHEMBL13624769 | 0.81 | STAT6 (0.66) | SYKSTAT6 | |
| SCHEMBL1353864 | 0.81 | SYK (1.00) | SYK | |
| SCHEMBL13624688 | 0.81 | STAT6 (0.67) | SYKSTAT6 | |
| SCHEMBL13624874 | 0.80 | SYK (0.72) | SYK | |
| SCHEMBL13624770 | 0.80 | SYK (0.72) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323993-B1 | 2,6-DIAMINO- PYRIMIDIN- 5-YL-CARBOXAMIDES AS SYK OR JAK KINASES INHIBITORS | PORTOLA PHARM INC (US) | 2015-06-03 | — | — | EP | disclosed |
| WO-2009136995-A2 | INHIBITORS OF SYK PROTEIN KINASE | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |