Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 15/20 | 0.67 |
| ▸ | SYK | P43405 | 5/20 | 0.67 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.63 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624769 | 0.92 | STAT6 (0.66) | STAT6SYK | |
| SCHEMBL13624688 | 0.91 | STAT6 (0.67) | STAT6SYK | |
| SCHEMBL13624767 | 0.89 | SYK (0.69) | STAT6SYK | |
| SCHEMBL16781773 | 0.87 | SYK (0.81) | SYK | |
| SCHEMBL13624768 | 0.86 | SYK (0.70) | STAT6SYK | |
| SCHEMBL14658828 | 0.85 | STAT6 (0.79) | STAT6SYK | |
| SCHEMBL2386576 | 0.81 | STAT6 (1.00) | STAT6SYK | |
| SCHEMBL1353893 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL1353889 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL13624653 | 0.80 | SYK (0.64) | STAT6SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323993-B1 | 2,6-DIAMINO- PYRIMIDIN- 5-YL-CARBOXAMIDES AS SYK OR JAK KINASES INHIBITORS | PORTOLA PHARM INC (US) | 2015-06-03 | — | — | EP | disclosed |
| US-20140200198-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2014-07-17 | — | — | US | disclosed |
| WO-2009136995-A2 | INHIBITORS OF SYK PROTEIN KINASE | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200198-A1 | BORON-CONTAINING SMALL MOLECULES | BTD, BCL6B, BBOX1 | STAT6 656/4885SYK 702/4885EML4 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.