Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.64 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275453 | 0.91 | NR3C1 (0.68) | NR3C1CYP11B1CYP11B2PGR | |
| SCHEMBL4275503 | 0.87 | NR3C1 (0.63) | NR3C1CYP11B1CYP11B2PGR | |
| SCHEMBL4278483 | 0.86 | NR3C1 (0.71) | NR3C1CYP11B1CYP11B2PGR | |
| SCHEMBL4282623 | 0.84 | NR3C1 (0.60) | NR3C1CYP11B1CYP11B2PGR | |
| SCHEMBL4281763 | 0.84 | NR3C1 (0.59) | NR3C1PGR | |
| SCHEMBL4277271 | 0.84 | NR3C1 (0.59) | NR3C1PGR | |
| SCHEMBL4277746 | 0.82 | NR3C1 (0.57) | NR3C1CYP11B1CYP11B2PGR | |
| SCHEMBL4280735 | 0.82 | NR3C1 (0.57) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL4277704 | 0.82 | NR3C1 (0.56) | NR3C1 | |
| SCHEMBL4279273 | 0.82 | NR3C1 (0.58) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622594-B2 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |