Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873186 | 0.90 | — | — | |
| SCHEMBL30132350 | 0.80 | TSHR (0.46) | TSHRHIF1ATRPV1FAAHALDH1A1 | |
| SCHEMBL10085844 | 0.80 | TSHR (0.46) | TSHRHIF1ATRPV1FAAHALDH1A1 | |
| SCHEMBL16600525 | 0.80 | TSHR (0.46) | TSHRHIF1ATRPV1FAAHTRPA1 | |
| SCHEMBL8487319 | 0.80 | TSHR (0.46) | TSHRHIF1ATRPV1FAAH | |
| SCHEMBL690898 | 0.80 | TSHR (0.46) | TSHRHIF1ATRPV1FAAH | |
| SCHEMBL1271400 | 0.79 | — | — | |
| SCHEMBL16306519 | 0.79 | — | — | |
| SCHEMBL10798330 | 0.79 | TRPV1 (0.50) | TRPV1TRPA1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL25850087 | 0.77 | ADH1B (0.46) | TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138511-A1 | LONG-ACTING Y2 AND/OR Y4 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2009-11-19 | — | — | WO | disclosed |