Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347952 | 1.00 | SLC10A2 (0.67) | SLC10A2 | |
| SCHEMBL348841 | 0.97 | SLC10A2 (0.64) | SLC10A2 | |
| SCHEMBL347797 | 0.96 | SLC10A2 (0.65) | SLC10A2 | |
| SCHEMBL349686 | 0.96 | SLC10A2 (0.63) | SLC10A2 | |
| SCHEMBL347586 | 0.94 | SLC10A2 (0.61) | SLC10A2 | |
| SCHEMBL348849 | 0.93 | SLC10A2 (0.58) | SLC10A2 | |
| SCHEMBL348588 | 0.92 | SLC10A2 (0.56) | SLC10A2 | |
| SCHEMBL347266 | 0.89 | SLC10A2 (0.55) | SLC10A2 | |
| SCHEMBL366859 | 0.83 | SLC10A2 (0.67) | SLC10A2 | |
| SCHEMBL348848 | 0.83 | SLC10A2 (0.52) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615536-B2 | 1,4-benzothiazepine 1,1-dioxide derivative, process for its preparation, medicaments comprising this compound, and use thereof as a hypolipidaemic | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-11-10 | — | — | US | disclosed |
| US-7615536-B2 | 1,4-benzothiazepine 1,1-dioxide derivative, process for its preparation, medicaments comprising this compound, and use thereof as a hypolipidaemic | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-11-10 | — | — | US | disclosed |
| EP-1907370-B1 | NOVEL 1,4-BENZOTHIAZEPINE-1,1-DIOXIDE DERIVATIVE HAVING IMPROVED PROPERTIES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUND, AND USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-02-25 | — | — | EP | disclosed |
| US-20080207592-A1 | Novel 1,4-benzothiazepine-1,1-dioxide derivative having improved properties, method for the production thereof, medicaments containing said compound, and use thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| US-20080207592-A1 | Novel 1,4-benzothiazepine-1,1-dioxide derivative having improved properties, method for the production thereof, medicaments containing said compound, and use thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| US-20080207534-A1 | 1,4-BENZOTHIAZEPINE 1,1-DIOXIDE DERIVATIVE, PROCESS FOR ITS PREPARATION, MEDICAMENTS COMPRISING THIS COMPOUND, AND USE THEREOF AS A HYPOLIPIDAEMIC | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| US-20080207534-A1 | 1,4-BENZOTHIAZEPINE 1,1-DIOXIDE DERIVATIVE, PROCESS FOR ITS PREPARATION, MEDICAMENTS COMPRISING THIS COMPOUND, AND USE THEREOF AS A HYPOLIPIDAEMIC | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| WO-2007009655-A1 | 1,4-BENZOTHIAZEPINE 1,1-DIOXIDE DERIVATIVE, PROCESS FOR ITS PREPARATION, MEDICAMENTS COMPRISING THIS COMPOUND, AND USE THEREOF AS A HYPOLIPIDAEMIC | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-01-25 | — | — | WO | disclosed |
| WO-2007009656-A2 | NOVEL 1,4-BENZOTHIAZEPINE-1,1-DIOXIDE DERIVATIVE HAVING IMPROVED PROPERTIES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUND, AND USE THEREOF | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207592-A1 | Novel 1,4-benzothiazepine-1,1-dioxide derivative having improved properties, method for the production thereof, medicaments containing said compound, and use thereof | CYP51A1, CPT1A, CYP4B1 | SLC10A2 1072/4885 |
| US-20080207534-A1 | 1,4-BENZOTHIAZEPINE 1,1-DIOXIDE DERIVATIVE, PROCESS FOR ITS PREPARATION, MEDICAMENTS COMPRISING THIS COMPOUND, AND USE THEREOF AS A HYPOLIPIDAEMIC | CYP51A1, CYP4B1, CPT1A | SLC10A2 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.