Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO2B1 | O94956 | 4/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 3/20 | 1.00 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.86 |
| ▸ | KDM1A | O60341 | 2/20 | 0.79 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.79 |
| ▸ | GSK3B | P49841 | 3/20 | 0.79 |
| ▸ | UBE2N | P61088 | 1/20 | 0.79 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.70 |
| ▸ | P4HB | P07237 | 1/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | XDH | P47989 | 1/20 | 0.68 |
| ▸ | DPP4 | P27487 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prunin SCHEMBL13904742 | 1.00 | SLCO2B1 (1.00) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 | |
| Prunin SCHEMBL29560212 | 1.00 | SLCO2B1 (1.00) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 | |
| Prunin SCHEMBL31233345 | 1.00 | SLCO2B1 (1.00) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 | |
| Prunin SCHEMBL29336352 | 1.00 | SLCO2B1 (1.00) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 | |
| Prunin SCHEMBL2532187 | 1.00 | SLCO2B1 (1.00) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 | |
| Prunin SCHEMBL318230 | 1.00 | SLCO2B1 (1.00) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 | |
| Prunin SCHEMBL1122487 | 1.00 | SLCO2B1 (1.00) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 | |
| Prunin SCHEMBL31233342 | 1.00 | SLCO2B1 (1.00) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 | |
| Prunin SCHEMBL318229 | 1.00 | SLCO2B1 (1.00) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 | |
| SCHEMBL29822818 | 0.93 | PTPN1 (0.88) | SLCO2B1PTPN1SYNJ2KDM1ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285797-A1 | USE OF INHIBITORS OF CYP2A6 FOR REGULATING NICOTINE METABOLISM | NICOGEN INC. (CA) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285797-A1 | USE OF INHIBITORS OF CYP2A6 FOR REGULATING NICOTINE METABOLISM | CYP2A6, CYP2B6, CYP2D6 | SLCO2B1 484/4885PTPN1 1499/4885SYNJ2 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.