Prunin

Prunin

SCHEMBL318230

O=C1C[C@@H](c2ccc(O)cc2)Oc2cc(OC3OC(CO)C(O)C(O)C3O)cc(O)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLCO2B1 O94956 4/20 1.00
PTPN1 P18031 3/20 1.00
SYNJ2 O15056 1/20 0.86
KDM1A O60341 2/20 0.79
CYP19A1 P11511 4/20 0.79
GSK3B P49841 3/20 0.79
UBE2N P61088 1/20 0.79
TRPA1 O75762 1/20 0.70
P4HB P07237 1/20 0.70
TRPV1 Q8NER1 1/20 0.70
PKM P14618 1/20 0.69
XDH P47989 1/20 0.68
DPP4 P27487 2/20 0.65
TDP1 Q9NUW8 3/20 0.62
CALM1 P0DP23 2/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
POLB P06746 1/20 0.62
CACNA1B Q00975 1/20 0.62
APBA1 Q02410 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prunin SCHEMBL13904742 1.00 SLCO2B1 (1.00) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1
Prunin SCHEMBL29560212 1.00 SLCO2B1 (1.00) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1
Prunin SCHEMBL31233345 1.00 SLCO2B1 (1.00) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1
Prunin SCHEMBL29336352 1.00 SLCO2B1 (1.00) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1
Prunin SCHEMBL2532187 1.00 SLCO2B1 (1.00) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1
Prunin SCHEMBL1122487 1.00 SLCO2B1 (1.00) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1
Prunin SCHEMBL13625098 1.00 SLCO2B1 (1.00) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1
Prunin SCHEMBL31233342 1.00 SLCO2B1 (1.00) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1
Prunin SCHEMBL318229 1.00 SLCO2B1 (1.00) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1
SCHEMBL29822818 0.93 PTPN1 (0.88) SLCO2B1PTPN1SYNJ2KDM1ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4108323-B1 STABILIZER FOR EMULSION COMPOSITION NAGASE VIITA CO LTD (JP) 2025-10-15 EP claimed
US-12311001-B2 Use of extracellular vesicles of Rhizoma Drynariae in preparation of medicine for treating orthopedic diseases The Third Affiliated Hospital of Guangzhou University of Chinese Medicine (CN) 2025-05-27 US claimed
US-20250000923-A1 USE OF EXTRACELLULAR VESICLES OF RHIZOMA DRYNARIAE IN PREPARATION OF MEDICINE FOR TREATING ORTHOPEDIC DISEASES The Third Affiliated Hospital of Guangzhou University of Chinese Medicine (CN) 2025-01-02 US claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
US-20230293416-A1 A stabilizer for an emulsion composition Hayashibara Co., Ltd. (JP) 2023-09-21 US claimed
WO-2023155398-A1 USE OF EXTRACELLULAR VESICLES OF RHIZOMA DRYNARIAE IN PREPARATION OF MEDICINE FOR TREATING ORTHOPEDIC DISEASES 广州中医药大学第三附属医院 2023-08-24 WO claimed
CN-116555379-A Use of alpha-L-rhamnosidase St-rRNA with high temperature resistance and methanol resistance and application thereof 集美大学 2023-08-08 CN claimed
CN-115851856-A Preparation process of pulutinine 成都欧康医药股份有限公司 2023-03-28 CN claimed
EP-4108323-A1 STABILIZER FOR EMULSION COMPOSITION Hayashibara Co., Ltd. (JP) 2022-12-28 EP claimed
CN-115135299-A Stabilizer for emulsified composition 株式会社林原 2022-09-30 CN claimed
US-7887868-B2 low-salt soy sauce having an antihypertensive effect; contains 3.55% or less by weight of sodium, 0.5% to 3.6% by weight of potassium, 0.05 to 20% by weight of at least one polyphenol KAO CORPORATION (JP) 2011-02-15 US claimed
US-20100316743-A1 INHIBITION OF THE FORMATION OF AGEs BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) 2010-12-16 US claimed
US-7727524-B2 Low sodium liquid seasoning with anti-hypertensive activity KAO CORPORATION (JP) 2010-06-01 US claimed
CN-101686954-A The inhibition that AGE forms BASF BEAUTY CARE SOLUTIONS F 2010-03-31 CN claimed
US-20090170928-A1 Synthesis of oligo/poly(catechins) and methods of use GOVERNMENT OF THE UNITED STATES 2009-07-02 US claimed
WO-2006116532-A2 SYNTHESIS OF OLIGO/POLY(CATECHINS) AND METHODS OF USE UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2006-11-02 WO claimed
US-6583118-B1 Administering glycosides or flavonoids such as apigenin as antiarthritic agents and to prevent glycoprotein exhaustion from chondrocytes KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 2003-06-24 US claimed
EP-0719554-A1 Chondroprotective flavonoids Kureha Chemical Industry Co., Ltd. (JP) 1996-07-03 EP claimed
EP-0633022-A2 Chondroprotective flavones KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-01-11 EP claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316743-A1 INHIBITION OF THE FORMATION OF AGEs AGER, GLA, S100A6 SLCO2B1 4631/4885PTPN1 2842/4885SYNJ2 3632/4885
US-20090170928-A1 Synthesis of oligo/poly(catechins) and methods of use POLI, PUF60, FABP3 SLCO2B1 596/4885PTPN1 3445/4885SYNJ2 2312/4885
US-20230293416-A1 A stabilizer for an emulsion composition PIGS, UGCG, GBA2 SLCO2B1 1209/4885PTPN1 1131/4885SYNJ2 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.