SCHEMBL13625186

SCHEMBL13625186

O=C(NC1CCCCC1)OCCCC1CCCCC1

nearest known ligand 0.91

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.91
NAAA Q02083 15/20 0.62
ASAH1 Q13510 1/20 0.57
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12195994 0.95 EPHX1 (1.00) EPHX1NAAAASAH1
SCHEMBL13625188 0.86 EPHX1 (0.78) EPHX1NAAAASAH1
SCHEMBL24905881 0.83 EPHX1 (0.69) EPHX1NAAA
SCHEMBL16699820 0.83 EPHX1 (0.69) EPHX1NAAA
SCHEMBL5597213 0.81 EPHX1 (0.67) EPHX1NAAA
SCHEMBL2801497 0.81 EPHX1 (0.67) EPHX1
SCHEMBL21059112 0.80 EPHX1 (0.69) EPHX1NAAA
SCHEMBL1314880 0.80 EPHX1 (0.64) EPHX1NAAAASAH1HPGD
SCHEMBL5597218 0.79 EPHX1 (0.64) EPHX1NAAA
SCHEMBL1827279 0.79 EPHX1 (0.64) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7622526-B2 Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material ESSILOR INTERNATIONAL (FR) 2009-11-24 US disclosed
US-7622526-B2 Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material ESSILOR INTERNATIONAL (FR) 2009-11-24 US disclosed