Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.75 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.75 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.75 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.75 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.75 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.75 |
| ▸ | CSF1R | P07333 | 1/20 | 0.75 |
| ▸ | FER | P16591 | 1/20 | 0.75 |
| ▸ | MARK3 | P27448 | 1/20 | 0.75 |
| ▸ | FLT4 | P35916 | 1/20 | 0.75 |
| ▸ | FLT3 | P36888 | 1/20 | 0.75 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.75 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.75 |
| ▸ | CLK2 | P49760 | 1/20 | 0.75 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.75 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.75 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.75 |
| ▸ | STK3 | Q13188 | 1/20 | 0.75 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.75 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31210155 | 0.97 | CDK2 (0.71) | CDK2DYRK1ADCLK1PRKD3MAP4K4 | |
| SCHEMBL4316858 | 0.86 | DCLK1 (1.00) | CDK2DYRK1ADCLK1PRKD3MAP4K4 | |
| SCHEMBL10112175 | 0.84 | DYRK1A (0.58) | CDK2DYRK1ADCLK1PRKD3MAP4K4 | |
| SCHEMBL11686272 | 0.83 | DCLK1 (0.71) | CDK2DYRK1ADCLK1PRKD3MAP4K4 | |
| SCHEMBL29549117 | 0.83 | MAP2K4 (0.61) | CDK2DYRK1ADCLK1PRKD3MAP4K4 | |
| SCHEMBL4215112 | 0.83 | MAP2K4 (0.61) | CDK2DYRK1ADCLK1PRKD3MAP4K4 | |
| SCHEMBL1513016 | 0.81 | FGFR1 (0.71) | CDK2DYRK1ADCLK1PRKD3MAP4K4 | |
| SCHEMBL4219256 | 0.79 | PDPK1 (0.54) | CDK2DYRK1ADCLK1PRKD3MAP4K4 | |
| SCHEMBL4217257 | 0.79 | AXL (0.58) | CDK2DYRK1ADCLK1PRKD3MAP4K4 | |
| SCHEMBL4224562 | 0.79 | LRRK2 (0.67) | CDK2DYRK1ADCLK1PRKD3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247392-A | Carbazolophenazinyl-containing compound, intermediate for preparing carbazolophenazinyl-containing compound and application of carbazolophenazinyl-containing compound | 阜阳欣奕华材料科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| US-8067447-B2 | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-11-29 | — | — | US | disclosed |
| US-20100076014-A1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076014-A1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | NFRKB, NFKBIA, NFKB1 | CDK2 3203/4885DYRK1A 1878/4885DCLK1 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.