Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627356 | 0.94 | TDP1 (0.79) | TDP1ABCB1MAPK1POLBPRKCA | |
| SCHEMBL17635918 | 0.94 | TDP1 (0.79) | TDP1ABCB1MAPK1POLBPRKCA | |
| SCHEMBL270042 | 0.88 | TDP1 (0.96) | TDP1ABCB1MAPK1POLBALDH1A1 | |
| SCHEMBL7154355 | 0.88 | TDP1 (0.88) | TDP1ABCB1MAPK1POLBALDH1A1 | |
| SCHEMBL7150717 | 0.88 | TDP1 (0.96) | TDP1ABCB1MAPK1POLBALDH1A1 | |
| SCHEMBL826717 | 0.88 | TDP1 (0.96) | TDP1ABCB1MAPK1POLBALDH1A1 | |
| SCHEMBL2175855 | 0.88 | TDP1 (0.96) | TDP1ABCB1MAPK1POLBALDH1A1 | |
| SCHEMBL7149374 | 0.88 | TDP1 (0.96) | TDP1ABCB1MAPK1POLBALDH1A1 | |
| SCHEMBL187068 | 0.88 | TDP1 (0.88) | TDP1ABCB1MAPK1POLBALDH1A1 | |
| SCHEMBL7146329 | 0.88 | TDP1 (0.88) | TDP1ABCB1MAPK1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133401-A1 | SYNTHESIS OF TIMOSAPONIN BII | PHYTOPHARM PLC (GB) | 2009-11-05 | — | — | WO | disclosed |