Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625474 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13625392 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14297006 | 0.80 | ALDH1A1 (0.45) | ALDH1A1HPGDRAB9ASMN1; SMN2LMNA | |
| SCHEMBL15074943 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL2833160 | 0.76 | AOC3 (0.53) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22876772 | 0.75 | POLB (0.44) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13892210 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13625979 | 0.74 | HPGD (0.46) | ALDH1A1HPGDLMNAPOLBHDAC3 | |
| SCHEMBL13625389 | 0.73 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL10780496 | 0.72 | PSMB11 (0.61) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |