Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355598 | 0.89 | TAAR1 (0.40) | TAAR1SLC6A4IDO1LMNAALOX12 | |
| SCHEMBL23316639 | 0.88 | TAAR1 (0.46) | TAAR1DAOPNMTIDO1LMNA | |
| SCHEMBL22149680 | 0.80 | TAAR1 (0.57) | TAAR1SLC6A4GAAKCNH2NPC1 | |
| SCHEMBL6740216 | 0.80 | TAAR1 (0.71) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL22480926 | 0.79 | TAAR1 (0.52) | TAAR1DAOIDO1LMNANPC1 | |
| SCHEMBL9921245 | 0.79 | MAPT (0.38) | TAAR1SLC6A4IDO1KCNH2RAB9A | |
| SCHEMBL9174302 | 0.78 | TAAR1 (0.35) | TAAR1SLC6A4IDO1LMNAALOX12 | |
| SCHEMBL10822907 | 0.78 | HPGD (0.36) | TAAR1SLC6A4IDO1LMNAALOX12 | |
| SCHEMBL18252847 | 0.78 | TAAR1 (0.59) | TAAR1PNMT | |
| SCHEMBL9174310 | 0.78 | IDO1 (0.42) | TAAR1SLC6A4IDO1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141637-A1 | A SENSOR | VIVACTA LTD (GB) | 2009-11-26 | — | — | WO | disclosed |