Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932525 | 0.89 | AMY1A (0.42) | IDO1LMNAALOX12SMN1; SMN2 | |
| SCHEMBL11194149 | 0.89 | LMNA (0.48) | TAAR1IDO1PNMTLMNAALOX12 | |
| SCHEMBL13625425 | 0.88 | TAAR1 (0.50) | TAAR1IDO1PNMTLMNAALOX12 | |
| SCHEMBL9718454 | 0.85 | LMNA (0.44) | TAAR1IDO1PNMTLMNAALOX12 | |
| SCHEMBL14600738 | 0.82 | CYP3A4 (0.46) | LMNA | |
| SCHEMBL30024296 | 0.82 | AMY1A (0.61) | IDO1LMNAALOX12SMN1; SMN2 | |
| SCHEMBL672407 | 0.80 | IDO1 (0.62) | TAAR1IDO1PNMTLMNADAO | |
| SCHEMBL29519238 | 0.80 | IDO1 (0.62) | TAAR1IDO1PNMTLMNADAO | |
| SCHEMBL28219402 | 0.79 | PLA2G7 (0.46) | TAAR1IDO1PNMTLMNAALOX12 | |
| SCHEMBL23119741 | 0.78 | SLC5A2 (0.41) | IDO1ALOX12PDE3BPDE3ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816158-B1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS IDH1 INHIBITORS | KPC PHARMACEUTICALS INC (CN) | 2023-10-25 | — | — | EP | disclosed |
| EP-3816158-A1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS IDH1 INHIBITORS | KPC Pharmaceuticals, Inc. (CN) | 2021-05-05 | — | — | EP | disclosed |