Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989632 | 0.78 | NPC1 (0.41) | CNR1CNR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2392906 | 0.78 | SMN1; SMN2 (0.45) | CNR1CNR2KCNQ2DRD4HTR2C | |
| SCHEMBL1411567 | 0.76 | RAB9A (0.44) | KDM4EUBE2MDCUN1D1KCNQ2DRD4 | |
| SCHEMBL8990113 | 0.75 | DRD4 (0.43) | CNR1CNR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8989648 | 0.74 | MEN1 (0.43) | CNR1CNR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17054715 | 0.73 | DRD4 (0.35) | KDM4EFFAR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1411897 | 0.73 | HPGD (0.43) | FFAR4KCNQ2DRD4 | |
| SCHEMBL12259689 | 0.73 | KMT2A (0.37) | — | |
| SCHEMBL1411444 | 0.73 | DRD4 (0.42) | KDM4EKCNQ2DRD4 | |
| SCHEMBL8988301 | 0.72 | KMT2A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137681-A1 | THERAPEUTICALLY USEFUL SUBSTITUTED HYDROPYRIDO [3,2,1-IJ] QUINOLINE COMPOUNDS | ALLERGAN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |