Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.49 |
| ▸ | STS | P08842 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577408 | 0.88 | SERPINE1 (0.60) | SERPINE1STSSMN1; SMN2LMNAMAPT | |
| SCHEMBL13015792 | 0.87 | HTT (0.49) | SERPINE1STSSMN1; SMN2LMNAMAPT | |
| SCHEMBL343297 | 0.86 | SERPINE1 (0.62) | SERPINE1STSSMN1; SMN2LMNAMAPT | |
| SCHEMBL112021 | 0.83 | MEN1 (0.56) | SERPINE1STSSMN1; SMN2LMNAMAPT | |
| SCHEMBL22432814 | 0.83 | SMYD3 (0.47) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL13625652 | 0.82 | SERPINE1 (0.44) | SERPINE1STSSMN1; SMN2LMNAMAPT | |
| SCHEMBL6857436 | 0.81 | SERPINE1 (0.58) | SERPINE1STSSMN1; SMN2LMNAMAPT | |
| SCHEMBL6857427 | 0.81 | SERPINE1 (0.58) | SERPINE1STSSMN1; SMN2LMNAMAPT | |
| SCHEMBL2611728 | 0.81 | SERPINE1 (0.53) | SERPINE1STSSMN1; SMN2LMNAMAPT | |
| SCHEMBL6851327 | 0.81 | SERPINE1 (0.58) | SERPINE1STSSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |