Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 3/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625650 | 0.82 | SERPINE1 (0.49) | SERPINE1CYP1A2CYP2D6HTR3EHTR3B | |
| SCHEMBL17941263 | 0.75 | KMT2A (0.45) | SERPINE1CYP2D6MEN1CYP2C19KMT2A | |
| SCHEMBL17941240 | 0.74 | STS (0.46) | SERPINE1KMT2ATSHRSTSLMNA | |
| SCHEMBL17941237 | 0.74 | STS (0.46) | SERPINE1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL16015361 | 0.74 | MEN1 (0.55) | SERPINE1CYP1A2CYP2D6HTR3EHTR3B | |
| SCHEMBL17941233 | 0.72 | SERPINE1 (0.45) | SERPINE1CYP1A2CYP2D6MEN1CYP2C19 | |
| SCHEMBL17941244 | 0.71 | ALOX15 (0.40) | SERPINE1CYP1A2CYP2D6MEN1CYP2C19 | |
| SCHEMBL13625648 | 0.71 | SERPINE1 (0.43) | SERPINE1MEN1KMT2APRKCAPRKCD | |
| SCHEMBL17941235 | 0.71 | SERPINE1 (0.41) | SERPINE1CYP1A2CYP2D6MEN1CYP2C19 | |
| SCHEMBL343297 | 0.71 | SERPINE1 (0.62) | SERPINE1CYP1A2CYP2D6HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |