Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145604 | 0.85 | KDM4E (0.42) | KDM4EPKMKLK7MEN1KMT2A | |
| SCHEMBL29997995 | 0.85 | KLK7 (0.46) | KDM4EPKMKLK7MEN1KMT2A | |
| SCHEMBL7297892 | 0.81 | KLK7 (0.47) | KDM4EPKMKLK7MEN1KMT2A | |
| SCHEMBL30718564 | 0.81 | MEN1 (0.45) | KDM4EPKMKLK7MEN1KMT2A | |
| SCHEMBL7869122 | 0.81 | KLK7 (0.41) | KDM4EPKMKLK7MEN1KMT2A | |
| SCHEMBL13586670 | 0.80 | KDM4E (0.42) | KDM4EPKMMEN1KMT2AGPR119 | |
| SCHEMBL29997845 | 0.78 | KLK7 (0.48) | KDM4EPKMKLK7MEN1KMT2A | |
| SCHEMBL5803438 | 0.77 | KCNH2 (0.46) | — | |
| SCHEMBL5803431 | 0.77 | KCNH2 (0.46) | — | |
| SCHEMBL2964414 | 0.77 | KCNH2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |