Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29997995 | 0.87 | KLK7 (0.46) | KLK7KDM4EPKMGPR119JAK2 | |
| SCHEMBL8908032 | 0.83 | KLK7 (0.47) | KLK7KDM4EPKMPARP1GPR119 | |
| SCHEMBL8907403 | 0.83 | KLK7 (0.47) | KLK7KDM4EPKMPARP1GPR119 | |
| SCHEMBL7869122 | 0.83 | KLK7 (0.41) | KLK7KDM4EPKMGPR119HCRTR2 | |
| SCHEMBL7301938 | 0.83 | KLK7 (0.47) | KLK7KDM4EPKMPARP1GPR119 | |
| SCHEMBL31228337 | 0.82 | KLK7 (0.46) | KLK7KDM4EPKMPARP1GPR119 | |
| SCHEMBL31228493 | 0.82 | KLK7 (0.46) | KLK7KDM4EPKMPARP1GPR119 | |
| SCHEMBL31228495 | 0.82 | KLK7 (0.46) | KLK7KDM4EPKMPARP1GPR119 | |
| SCHEMBL13625747 | 0.81 | KDM4E (0.42) | KLK7KDM4EPKMGPR119HCRTR2 | |
| SCHEMBL145604 | 0.81 | KDM4E (0.42) | KLK7KDM4EPKMGPR119STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |