Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116260 | 1.00 | MEN1 (0.42) | MEN1KMT2AALDH1A1TSHRCTSL | |
| SCHEMBL14294773 | 1.00 | MEN1 (0.42) | MEN1KMT2AALDH1A1TSHRCTSL | |
| SCHEMBL2572675 | 1.00 | MEN1 (0.42) | MEN1KMT2AALDH1A1TSHRCTSL | |
| SCHEMBL18336025 | 1.00 | MEN1 (0.42) | MEN1KMT2AALDH1A1TSHRCTSL | |
| SCHEMBL13625758 | 1.00 | MEN1 (0.42) | MEN1KMT2AALDH1A1TSHRCTSL | |
| SCHEMBL38660321 | 0.87 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRCTSL | |
| SCHEMBL116483 | 0.87 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRCTSL | |
| SCHEMBL25204927 | 0.86 | MEN1 (0.44) | MEN1KMT2AALDH1A1TSHRCTSL | |
| SCHEMBL5319920 | 0.86 | CHRM2 (0.42) | CHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL15690447 | 0.86 | CHRM2 (0.42) | CHRM2CHRM1CHRM3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |