Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 4/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141426 | 0.89 | ADRB2 (0.45) | ADRB2KMT2AMEN1STAT3TOP2A | |
| SCHEMBL149073 | 0.89 | ADRB2 (0.45) | ADRB2KMT2AMEN1STAT3TOP2A | |
| SCHEMBL116323 | 0.89 | ADRB2 (0.45) | ADRB2KMT2AMEN1STAT3TOP2A | |
| SCHEMBL145085 | 0.88 | ADRB2 (0.46) | ADRB2KMT2AMEN1STAT3TOP2A | |
| SCHEMBL146707 | 0.88 | ADRB2 (0.46) | ADRB2KMT2AMEN1STAT3TOP2A | |
| SCHEMBL178720 | 0.86 | ADRB2 (0.49) | ADRB2KMT2AMEN1STAT3TOP2A | |
| SCHEMBL144356 | 0.86 | ADRB2 (0.44) | ADRB2KMT2AMEN1STAT3TOP2A | |
| SCHEMBL144925 | 0.86 | ADRB2 (0.44) | ADRB2KMT2AMEN1STAT3TOP2A | |
| SCHEMBL143930 | 0.86 | ADRB2 (0.44) | ADRB2KMT2AMEN1STAT3TOP2A | |
| SCHEMBL144893 | 0.86 | ADRB2 (0.44) | ADRB2KMT2AMEN1STAT3TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |