Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PRKDC | P78527 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28281706 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL5698339 | 0.79 | ALDH1A1 (0.81) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL25142653 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL20525308 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL9723475 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL30148031 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL2432873 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL9039124 | 0.75 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| Asaraldehyde SCHEMBL333451 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| Asaraldehyde SCHEMBL29456596 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4ETSHRTDP1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138665-A1 | METHODS FOR ASYMMETRICALLY SYNTHESIZING 6-FLUORO-L-DOPA AND ANALOGS THEREOF | LABORATOIRES CYCLOPHARMA (FR) | 2009-11-19 | — | — | WO | disclosed |