Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146868 | 0.84 | ALDH1A1 (0.52) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL13626261 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL16204631 | 0.77 | ABCB1 (0.51) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL140115 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL143840 | 0.76 | ABCB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL19942968 | 0.76 | ABCB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL26503908 | 0.76 | ABCB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL18342378 | 0.76 | ABCB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL20480178 | 0.76 | ABCB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL25551199 | 0.76 | ABCB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |