Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.71 |
| ▸ | PTGFR | P43088 | 7/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10103935 | 0.93 | ABCB11 (0.75) | ABCB11AKR1C3PTGFRPTGER3PTGER1 | |
| SCHEMBL15151300 | 0.92 | ABCB11 (0.70) | ABCB11AKR1C3PTGFRPTGER3PTGER1 | |
| SCHEMBL10112558 | 0.92 | ABCB11 (0.70) | ABCB11AKR1C3PTGFRPTGER3PTGER1 | |
| SCHEMBL397553 | 0.91 | ABCB11 (0.77) | ABCB11AKR1C3PTGFRPTGER3PTGER1 | |
| SCHEMBL397551 | 0.91 | ABCB11 (0.77) | ABCB11AKR1C3PTGFRPTGER3PTGER1 | |
| SCHEMBL10103984 | 0.91 | ABCB11 (0.77) | ABCB11AKR1C3PTGFRPTGER3PTGER1 | |
| SCHEMBL461197 | 0.91 | ABCB11 (0.77) | ABCB11AKR1C3PTGFRPTGER3PTGER1 | |
| SCHEMBL397552 | 0.91 | ABCB11 (0.77) | ABCB11AKR1C3PTGFRPTGER3PTGER1 | |
| SCHEMBL13960687 | 0.91 | ABCB11 (0.78) | ABCB11AKR1C3PTGFRPTGER3PTGER1 | |
| SCHEMBL399395 | 0.91 | ABCB11 (0.67) | ABCB11AKR1C3PTGFRPTGER3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136281-A1 | NITRIC OXIDE DONATING PROSTAMIDES | NICOX S.A. (FR) | 2009-11-12 | — | — | WO | disclosed |