Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25907340 | 0.91 | CPB1 (0.53) | CPB1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL32672364 | 0.91 | CPB1 (0.53) | CPB1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18337377 | 0.85 | CPB1 (0.48) | CPB1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23270785 | 0.84 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1FKBP1A | |
| SCHEMBL1515645 | 0.84 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1FKBP1A | |
| SCHEMBL29302827 | 0.84 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1FKBP1A | |
| SCHEMBL16142834 | 0.84 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1FKBP1A | |
| SCHEMBL116480 | 0.84 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1FKBP1A | |
| SCHEMBL34466990 | 0.84 | PDE4B (0.49) | CPB1ALDH1A1CTSLFKBP1ATSHR | |
| SCHEMBL116516 | 0.83 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2FKBP1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |