Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 3/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12112294 | 1.00 | PTGER2 (0.52) | PTGER2PTGER3PTGDRACHEALDH1A1 | |
| SCHEMBL16480454 | 0.85 | NPC1 (0.49) | PTGER2PTGER3ALDH1A1CNR2CYP2C8 | |
| SCHEMBL13626380 | 0.83 | CNR2 (0.45) | PTGER2PTGER3PTGDRCNR2CYP2C8 | |
| SCHEMBL4636834 | 0.81 | GAA (0.46) | KMT2ACCNA2CDK2CCNA1SLC6A2 | |
| SCHEMBL13109278 | 0.80 | PTGER2 (0.52) | PTGER2PTGER3PTGDRALDH1A1CNR2 | |
| SCHEMBL12112292 | 0.80 | PTGER2 (0.52) | PTGER2PTGER3PTGDRALDH1A1CNR2 | |
| SCHEMBL25416662 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KMT2ACCNA2CDK2CCNA1 | |
| SCHEMBL10131414 | 0.79 | CYP3A4 (0.41) | CYP2C9CYP2C19KMT2ACCNA2CDK2 | |
| SCHEMBL22658820 | 0.79 | SLC6A2 (0.46) | ACHEALDH1A1CNR2KMT2ACCNA2 | |
| SCHEMBL16480393 | 0.79 | TDP1 (0.47) | CNR2CYP2C19KMT2ACCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286787-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286787-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | GLA, GUSB, GANAB | PTGER2 3210/4885PTGER3 2745/4885PTGDR 1340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.