SCHEMBL13626419

SCHEMBL13626419

CNc1ncnn2c(C3CCC3)nc(-c3ccc(C(=O)c4ccccc4)cc3F)c12

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 19/20 0.77
MTOR P42345 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4364064 0.87 TNK2 (1.00) TNK2
SCHEMBL4357735 0.74 TNK2 (1.00) TNK2
SCHEMBL4353507 0.72 TNK2 (1.00) TNK2
SCHEMBL14536893 0.68 MTOR (0.68) TNK2MTOR
SCHEMBL4362526 0.67 TNK2 (1.00) TNK2
SCHEMBL4368927 0.67 TNK2 (1.00) TNK2
SCHEMBL4364079 0.67 TNK2 (1.00) TNK2
SCHEMBL23847741 0.66 TNK2 (0.69) TNK2
SCHEMBL4353081 0.66 TNK2 (1.00) TNK2
SCHEMBL4362665 0.65 TNK2 (1.00) TNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009143051-A1 SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES OSI PHARMACEUTICALS, INC. (US) 2009-11-26 WO disclosed