Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 11/20 | 0.49 |
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127101 | 0.81 | FGFR3 (0.70) | FGFR3F10 | |
| SCHEMBL17023036 | 0.74 | FGFR3 (0.55) | FGFR3F10CHEK1 | |
| SCHEMBL1126353 | 0.73 | FGFR3 (0.81) | FGFR3 | |
| SCHEMBL3317617 | 0.71 | FGFR3 (0.50) | FGFR3CHEK1 | |
| SCHEMBL1126391 | 0.70 | FGFR3 (0.75) | FGFR3 | |
| SCHEMBL3316242 | 0.69 | FGFR3 (0.51) | FGFR3 | |
| SCHEMBL14217248 | 0.67 | FGFR3 (0.56) | FGFR3 | |
| SCHEMBL12678322 | 0.67 | FGFR3 (0.83) | FGFR3 | |
| SCHEMBL1126624 | 0.66 | FGFR3 (1.00) | FGFR3 | |
| SCHEMBL12678327 | 0.66 | FGFR3 (1.00) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141386-A1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2009-11-26 | — | — | WO | disclosed |