Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 18/20 | 0.64 |
| ▸ | INSR | P06213 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626519 | 0.82 | TNK2 (0.79) | TNK2IGF1R | |
| SCHEMBL4356809 | 0.78 | TNK2 (1.00) | TNK2IGF1R | |
| SCHEMBL4354150 | 0.76 | TNK2 (1.00) | TNK2INSRIGF1R | |
| SCHEMBL13618402 | 0.76 | TNK2 (0.81) | TNK2IGF1R | |
| SCHEMBL4354145 | 0.76 | TNK2 (1.00) | TNK2INSRIGF1R | |
| SCHEMBL399845 | 0.74 | IGF1R (0.79) | TNK2INSRIGF1R | |
| SCHEMBL3297980 | 0.73 | IGF1R (0.59) | TNK2INSRIGF1R | |
| SCHEMBL13812491 | 0.72 | IGF1R (0.48) | TNK2INSRIGF1R | |
| SCHEMBL13626878 | 0.72 | TNK2 (0.78) | TNK2 | |
| SCHEMBL400580 | 0.71 | IGF1R (0.59) | TNK2INSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143051-A1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |