SCHEMBL13626519

SCHEMBL13626519

Nc1ncnn2c(C3CC(O)C3)nc(-c3ccc(Cc4ccccc4)cc3)c12

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 19/20 0.79
IGF1R P08069 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4364422 0.85 TNK2 (1.00) TNK2IGF1R
SCHEMBL3297980 0.82 IGF1R (0.59) TNK2IGF1R
SCHEMBL13626520 0.82 TNK2 (0.64) TNK2IGF1R
SCHEMBL399845 0.79 IGF1R (0.79) TNK2IGF1R
SCHEMBL8240001 0.79 TNK2 (0.83) TNK2IGF1R
SCHEMBL13626521 0.78 TNK2 (0.82) TNK2IGF1R
SCHEMBL3296711 0.77 IGF1R (0.57) TNK2IGF1R
SCHEMBL400580 0.77 IGF1R (0.59) TNK2IGF1R
SCHEMBL13560232 0.76 TNK2 (0.83) TNK2
SCHEMBL4360053 0.75 TNK2 (0.61) TNK2IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009143051-A1 SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES OSI PHARMACEUTICALS, INC. (US) 2009-11-26 WO disclosed