Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626110 | 0.81 | LTB4R2 (0.43) | LTB4R2FFAR1AKR1B1MYCWDR5 | |
| Hydrochloric Acid SCHEMBL9844253 | 0.76 | LTB4R2 (0.47) | LTB4R2FFAR1AKR1B1MYCWDR5 | |
| SCHEMBL2692039 | 0.73 | PPARG (0.53) | FFAR1AKR1B1ACHEPPARGESR2 | |
| SCHEMBL6606543 | 0.72 | HRH4 (0.54) | MYCWDR5ACHEPPARGMME | |
| SCHEMBL4253889 | 0.72 | HSD17B10 (0.58) | FFAR1AKR1B1ACHEKDM4EPPARG | |
| SCHEMBL14207515 | 0.72 | MYC (0.37) | LTB4R2MYCWDR5ACHEPPARG | |
| SCHEMBL6954317 | 0.71 | HSD17B10 (0.60) | FFAR1AKR1B1ACHEKDM4EPPARG | |
| SCHEMBL6954649 | 0.71 | HSD17B10 (0.60) | FFAR1AKR1B1ACHEKDM4EPPARG | |
| SCHEMBL10718048 | 0.71 | HSD17B10 (0.60) | FFAR1AKR1B1ACHEKDM4EPPARG | |
| SCHEMBL4256521 | 0.71 | HSD17B10 (0.60) | FFAR1AKR1B1ACHEKDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |