SCHEMBL4253889

SCHEMBL4253889

CCCCCc1ccc(-c2ccccc2C#N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.58
TSHR P16473 1/20 0.58
PPARG P37231 2/20 0.52
ESR2 Q92731 1/20 0.51
ACHE P22303 1/20 0.49
FFAR1 O14842 1/20 0.48
AKR1B1 P15121 1/20 0.48
AGTR1 P30556 3/20 0.47
AGTR2 P50052 2/20 0.47
HSD11B1 P28845 3/20 0.47
ALDH1A1 P00352 2/20 0.46
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.46
CASP3 P42574 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6954317 0.98 HSD17B10 (0.60) HSD17B10TSHRPPARGESR2ACHE
SCHEMBL4256521 0.98 HSD17B10 (0.60) HSD17B10TSHRPPARGESR2ACHE
SCHEMBL6954649 0.98 HSD17B10 (0.60) HSD17B10TSHRPPARGESR2ACHE
SCHEMBL10718048 0.98 HSD17B10 (0.60) HSD17B10TSHRPPARGESR2ACHE
SCHEMBL2692039 0.95 PPARG (0.53) HSD17B10TSHRPPARGESR2ACHE
SCHEMBL6961928 0.89 PPARG (0.59) HSD17B10TSHRPPARGESR2ACHE
SCHEMBL10576688 0.88 HSD17B10 (0.55) HSD17B10TSHRPPARGACHEHSD11B1
SCHEMBL4257929 0.86 TSHR (0.50) HSD17B10TSHRPPARGACHEFFAR1
SCHEMBL6957868 0.86 ESR2 (0.57) HSD17B10TSHRPPARGESR2ACHE
SCHEMBL6033048 0.84 HSD17B10 (0.77) HSD17B10TSHRACHEHSD11B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6821457-B1 PHOTOPOLYMERIZABLE PENTAACRYLATE, CHAIN EXTENDER, INITIATORS, AND CROSSLINKING AGENT; SINGLE STEP, FAST RECORDING OF VOLUME HOLOGRAMS; TRANSMISSION GRATINGS SCIENCE APPLICATIONS INTERNATIONAL CORPORATION 2004-11-23 US claimed
US-4083797-A ALKYLCYANO-BIPHENYL TYPE, ESTER AND CHLORO-SUBSTITUTED DIESTER TYPES BECKMAN INSTRUMENTS, INC. (US) 1978-04-11 US claimed
US-12197059-B2 System with salt-based color adjustment of substrate BIC Violex Single Member S.A. (GR) 2025-01-14 US disclosed
US-20240099985-A1 LIQUID CRYSTAL-INFUSED POROUS SURFACES AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION 2024-03-28 US disclosed
US-20230314858-A1 SYSTEM WITH SALT-BASED COLOR ADJUSTMENT OF SUBSTRATE BIC Violex Single Member S.A. (GR) 2023-10-05 US disclosed
EP-4253077-A1 SYSTEM WITH SALT-BASED COLOR ADJUSTMENT OF SUBSTRATE BIC Violex Single Member S.A. (GR) 2023-10-04 EP disclosed
US-11617969-B2 Activated release of target material trapped in anisotropic fluids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-04-04 US disclosed
EP-4121816-A1 ELECTROCHROMIC DEVICE AND METHOD FOR PRODUCING THE SAME Freshape SA (CH) 2023-01-25 EP disclosed
WO-2021185999-A1 ELECTROCHROMIC DEVICE AND METHOD FOR PRODUCING THE SAME H.GLASS SA (CH) 2021-09-23 WO disclosed
US-20190329155-A1 Activated Release of Target Material Trapped in Anisotropic Fluids NATIONAL SCIENCE FOUNDATION 2019-10-31 US disclosed
WO-2017218635-A2 ACTIVATED RELEASE OF TARGET MATERIAL TRAPPED IN ANISOTROPIC FLUIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-12-21 WO disclosed
EP-1673646-A2 LIQUID CRYSTAL MATERIALS AND ELECTROOPTIC DEVICES WITH A LIQUID CRYSTAL-CONTAINING CLADDING Optimer Photonics, Inc. (US) 2006-06-28 EP disclosed
WO-2005113866-A1 A FILAMENT OR FIBRE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2005-12-01 WO disclosed
WO-2005038497-A2 LIQUID CRYSTAL MATERIALS AND ELECTROOPTIC DEVICES WITH A LIQUID CRYSTAL-CONTAINING CLADDING OPTIMER PHOTONICS, INC. (US) 2005-04-28 WO disclosed
EP-0219187-A1 Non-coherent frequency source and sector scanning apparatus for ultrasonic imaging system using a liquid crystal detector cell Raj Technology, Inc. (US) 1987-04-22 EP disclosed
EP-0142617-A1 Pleochroic anthraquinone dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-05-29 EP disclosed
EP-0047453-B1 4'-(BETA-ALKYLOXYETHOXY)-4-CYANOBIPHENYL Chisso Corporation (JP) 1984-02-08 EP disclosed
US-4374748-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1983-02-22 US disclosed
EP-0047453-A1 4'-(Beta-alkyloxyethoxy)-4-cyanobiphenyl Chisso Corporation (JP) 1982-03-17 EP disclosed
US-4083797-A ALKYLCYANO-BIPHENYL TYPE, ESTER AND CHLORO-SUBSTITUTED DIESTER TYPES BECKMAN INSTRUMENTS, INC. (US) 1978-04-11 US disclosed